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Master Student (m/f/d) Department Adipocyte Development and Nutrition
Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke
The German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE) is a member of the Leibniz association. The institute's mission is to conduct experimental
and clinical research in the field of nutrition and health, with the aim of understanding the molecular basis of nutrition-dependent diseases, and of developing new strategies for
treatment and prevention (Website: http://www.dife.de/?lang=en).
The Department Adipocyte Development and Nutrition (ADE) is inviting applications for
1 Master Student (m/f/d) / Department Adipocyte Development and Nutrition
in Nuthetal OT Bergholz-Rehbrücke
on the topic: Analysis of the effects of aging and metabolic diseases on the composition of the stem cell niche
In addition to the classic fat depots (the white and the brown fat) there is also a so-called ectopic fat storage. Ectopic fat cells have been implicated in a number of functional
and metabolic disorders in a number of tissues. Ectopic fat cells arise from a population of specialized cells called mesenchymal stem or stromal cells (MSCs). It is assumed that MSCs
increasingly undergo an adipogenic differentiation with old age and in this way may increasingly promote ectopic fatty cell formation thereby contributing to pathological processes and
impaired regeneration. In addition to single-cell analysis, this master's thesis deals with the in vivo manipulation of the identified genes with the aim of improving health in old age
and in metabolic disease states.
RNA isolation from cell samples, qPCR quantification of gene expression and use of relevant software (Office Suite, BioRad PrimePCR and Prism)
Cell culture and investigation of cell differentiation
Evaluation and analysis of results
The institute offers a vibrant and interactive research environment and expects interested and committed candidates.
Application will be considered on an ongoing basis until the pot has been filled. Please send your application documents before 31.10.2019 to:
German Institute of Human Nutrition Potsdam-Rehbrücke
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