The Department of Hematology and Cell Therapy (Director: Prof. Uwe Platzbecker) in the Medical Clinic and Policlinic I, Leipzig University Hospital, invites applications for a

Post-Doc in Experimental Hematology

to lead a research group investigating the regulatory environment of the osteohematopoietic niche. This work will focus on myelodysplasia and the translation of basic research into clinical applications by:

• deciphering the role played by the microenvironment in bone marrow failure;
• characterizing the determinants of pre-leukemic and leukemic transformation;
• identifying novel drug targets;
• establishing drug-screening platforms, including pre-clinical models.

The successful candidate will have:

• a Ph.D. and/or M.D. with post-doctoral experience in hematology or a closely related field
• a strong record of high impact research in molecular cell biology/biochemistry and preferably in the use of in vivo models
• the ability to secure independent research funding
• good interpersonal, team and communication skills
• proficiency in spoken and written English

Additional experience in flow cytometry, next generation sequencing, ChIPseq, Hi-C, bioinformatics, computer modelling, and single cell techniques would be an advantage. This position is available for 3 years in the first instance, with a potential tenure track option thereafter. The Department of Hematology and Cell Therapy combines an innovative clinical hematology program with cutting edge research into the mechanisms of normal and malignant hematopoiesis and we are looking for a highly motivated individual who will make maximum use of our excellent facilities and productive, highly interactive research environment. We strongly encourage translational research and the applicant will be expected to take advantage of the extensive opportunities for interdisciplinary collaboration offered both locally and internationally and to contribute actively to the German MDS and EMSCO study group (www.emsco.eu). Applications should be submitted directly to Prof. Dr. Uwe Platzbecker, (uwe.platzbecker@medizin.uni-leipzig.de) and must include: a cover letter including a brief description of previous research experience and your motivation for applying to this position; a concise description of your research interests and plans (max 2 pages); your curriculum vitae with a list of publications and funding; a certified copy of your doctoral certificate and the contact details of two referees. The closing date for applications is March 31^th 2019 Female applicants are encouraged to apply and will be given preference in cases of equal aptitude, ability, and professional achievements unless there are exceptional reasons for choosing another applicant. Applications from suitably qualified severely disabled persons or disabled persons regarded as being of equal status according to Book IX of the German Social Legal Code (SGB-Soziales Gesetzbuch) are encouraged.