The Division for Molecular Virology of Human Infectious Diseases at the University Hospital Tübingen, Germany (Prof. Dr. Michael Schindler), invites candidates to apply for a vacancy with the following project:

Postdoc/PhD Student in Molecular Virology

- to study intracellular trafficking and release of hepatitis c virus
- to functionally characterize and optimize a novel pan-flavivirus inhibitor.
We have open positions in both projects for PhD students or a Postdoc which are initially funded for 36 months by the DFG and the BW Stiftung. The project aiming to delineate intracellular transport and release of HCV involves advanced super-resolution live cell fluorescence imaging in our BSL-3 facility. Therefore, experience with live cell imaging and the according data handling would be an asset. Furthermore, we have set up novel techniques to identify and characterize viral protein interactions. Advantageous, but not mandatory, is a background in:

• HCV virological assays
• live cell imaging
• basic molecular biology techniques (PCR, cloning)

The work on our novel pan-flavivirus inhibitor is a very interdisciplinary project embedded at the border between molecular virology and structural biology/pharmaceutical chemistry. We aim to optimize our primary hit by rationale-based SAR involving structural characterization, in silico modelling and resistance screening. Advantageous is a background in:

• HCV virological assays
• Structural biology
• basic molecular biology techniques (PCR, cloning)

This is an opportunity to work together with a vibrant team in a productive and stimulating environment and to perform research on an exciting and highly relevant topic. We seek highly motivated candidates with a strong dedication to science. If you would like to join us in combating viral human diseases, please send your application as one PDF file (Letter of motivation, CV, degrees and certificates, reference letters) preferentially by E-mail.
We offer remuneration in accordance with TV-L (collective wage agreement for the Public Service of the German Federal States) in addition to all the customary benefits granted to employees working in Public Services. Severely handicapped persons with equal qualifications are given preferential consideration. The University of Tübingen is anxious to increase its quota of female scientific staff, and therefore emphatically requests women to apply for this position. The Administration of the University Hospital is responsible for all employment matters. Personnel appointments will be made pursuant to the fundamental stipulations of the legal statutes for universities in Germany. Interview expenses are not covered. For further information, please contact Prof. Dr. Michael Schindler, Tel.: +49 (0) 7071 29- 87459, e-mail: michael.schindler@med.uni-tuebingen.de. Application deadline: May 31st, 2018. Please send your application with the reference number 8710 to:
Universitätsklinikum Tübingen
Institut für Medizinische Virologie und Epidemiologie der Viruskrankheiten
Herr Prof. Dr. Michael Schindler
Elfriede-Aulhorn-Str. 6
72076 Tübingen